Strategy

UK Urged To Protect R&D Tax Credits, The Lifeblood Of Biotechs

 
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Verona Pharma is rising high with the newly-launched chronic obstructive pulmonary disease drug Ohtuvayre but its development would have been severely compromised if it had not been for government benefits, non-executive chair David Ebsworth tells Scrip.

Coherus Continues Funding IO Ambitions By Offloading Biosimilars

 
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Coherus agreed to sell its biosimilar of Amgen’s Neulasta to Intas in a deal that will clear significant near-term debt and provide funds for a label-expansion strategy for its PD-1 agent Loqtorzi.

Sweden’s Alligator Makes Cuts To Avoid Extinction

 
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The company’s CD40 agonist mitazalimab has impressed in Phase II trials as a potential treatment for pancreatic cancer but with no partner in place yet and a lack of funds, Alligator has to cut 70% of its staff to keep going.

Abingworth Tight-Lipped On $1.5bn Clinical Trials Fund Reports

 
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The Carlyle-backed venture capital group is said to be working on a new fund to help finance up to eight late-stage clinical studies through potential partnerships with big pharma for a share of royalties. The move would be in keeping with its recent investment activities.


Broad Benefits Of Immunic MS Drug Could Transform Treatment

 
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While most drug development in the multiple sclerosis space has focused just on relapse prevention, Immunic’s dual-acting therapy vidofludimus calcium also offers a novel approach for neurodegeneration, its CEO Daniel Vitt tells Scrip.

Vabysmo Hopes To Ride New Coverage In China, Data To Expand In Asia

 

Roche's blockbuster ophthalmic drug set for China reimbursement list inclusion in three indications and shows positive interim results in PCV.

BIOSECURE Nudges Celltrion’s Jump Into CDMO Business

 
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Celltrion Group chairman outlines new plans for the Korean biosimilars giant to move into the CDMO sector and updates on new drug development activities.

Nykode Bruised But Not Broken After Roche Split

 
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The Norwegian biotech is losing a big pharma partner and up to half of its staff, but remains confident about the prospects for its personalized cancer vaccine programs.


Idorsia And Medigene Cut Jobs To Keep Going

 

Both companies are seeking to license their products as they try to stretch their dwindling cash.

Saniona Cash Worries Ease With Acadia Neuro Biobucks Pact

 
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Deal Snapshot: The essential tremor space has not seen innovation in treatment for decades. Acadia believes Saniona's GABAA-α3 positive allosteric modulator could be the answer.

Novartis Benefits From Biotech Lessons Taught By Development Head Aradhye

 
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The Swiss major’s chief medical officer tells Scrip about how “an R&D/commercial continuum” is helping to speed up innovation across the group.

Novartis Ups Sale Guidance And Heralds Rejuvenated Pipeline

 
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CEO Vas Narasimhan has highlighted the strong momentum from six new products plus the old favorites Entresto and Cosentyx, saying that there are over 30 high-value medicines in the pipeline that will drive continued mid-single digit sales growth beyond 2029.


Neurogene’s Value Tanks On Gene Therapy Side-Effect Details

 

The company is trading below cash after admitting that an adverse event in a Rett syndrome trial left a patient critically ill.

Q2 Results: What Top Indian Firms Said On China, Deal Appetite, GLP-1s

 

Sun and other major Indian firms outline how things are shaping up for products and manufacturing in China - while it’s a mixed bag, the wider outlook is upbeat. M&A and GLP-1 plays were among other key areas discussed during Q2 earnings.

Grifols Could Be Set For More Turmoil With Imminent €7bn Takeover Bid

 
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After completing due diligence, private equity firm Brookfield is reportedly close to launching an offer of €10.50 euros per share to acquire the Spanish major. Given that at least one investor believes Grifols is worth at least €20 a share, sparks could fly.

Halozyme Bid For Evotec Does Not Look High Enough

 
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The US firm wants to hook up with the German group to create a global innovative services company but its €11.00 per share cash offer looks unlikely to sway Evotec shareholders.


Korea Q3 Results Roundup: Lazertinib Boosts Yuhan, Hanmi Dispute Simmers

 
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Yuhan eyes successors to lazertinib after US approval, leadership dispute at Hanmi drags on and SK Bioscience completes CDMO acquisition.

Bayer Will Not Take Risky Bets To Close Xarelto Revenue Gap

 
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The German major’s CEO Bill Anderson will not be tempted to go out and make a big bid on a late-stage asset to fill the revenue gap caused by Xarelto’s patent expiries, telling Scrip that " in the pharma business, that's pretty much worse than going to the casino.”

Muscling Into The Obesity Market

 

At a recent conference, executives from Boehringer and Amgen laid out their expectations for the future of obesity and how they intend to navigate the changes.

Almirall Insists Costly Ebglyss Launch Is Progressing Well

 
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The Spanish company's Lilly-partnered atopic dermatitis drug is enjoying a decent launch in Germany and in other European countries, "we are getting the price that we wanted," claims CEO Carlos Gallardo.