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NHS England Backs Biosimilar-To-Biosimilar Switching As It Counts Adalimumab Savings

 
• By Aidan Fry

Switching between biosimilars does not appear to raise safety concerns, according to NHS England, which is anticipating more than £300m in annual savings from biosimilar competition on adalimumab.

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Multiple switches between biosimilars do not raise safety concerns. NHS England has stated in a briefing document on adalimumab • Source: Shutterstock

Real-world evidence shows that switching between biosimilars does not raise safety or efficacy concerns, a National Health Service briefing document on adalimumab has advised prescribers. By using the best-value adalimumab product available, NHS England expects to save more than £300m ($370m) in its current financial year, equivalent to about three-quarters of its historical spending on reference brand Humira.

An updated briefing by NHS England’s Regional Medicines Optimisation Committee recognizes the theoretical concerns around immunogenicity with biosimilar-to-biosimilar switching

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