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Alvotech Reveals Positive Data For Stelara Rival

Results For AVT04 Ustekinumab Biosimilar Come Ahead Of Oaktree SPAC Merger Vote

 
• By Dave Wallace

Alvotech has reported positive results from a study for its AVT04 proposed biosimilar ustekinumab rival to Stelara. The news comes ahead of a key vote on Alvotech’s SPAC merger with Oaktree Capital Management that will take the company public.

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Stelara represents a $9bn target for Alvotech • Source: Shutterstock

Alvotech has reported positive results from a key study for its AVT04 proposed biosimilar to Stelara (ustekinumab), with pharmacokinetic similarity data demonstrating equivalence to the reference brand.

The single-dose, three-arm, parallel-design PK similarity study was conducted in Australia and New Zealand with 294 healthy adult volunteers. It compared pharmacokinetics, safety, tolerability, and immunogenicity of a single 45mg/0.5ml subcutaneous dose of AVT04 with US-licensed as well as EU-approved versions of Stelara

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