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Humira In 2023: The $17bn Biosimilar Opportunity

Landmark LOE Looms In US; Several Adalimumab Launches Expected Throughout Year

 
• By Dave Wallace

The advent of US biosimilar competition to Humira in 2023 represents the largest ever loss-of-exclusivity opportunity for the off-patent industry, with the first adalimumab rival expected to hit the US market at the end of this month. But with a host of other biosimilars expected to launch throughout the year, how will competition play out in the long term?

2023 Dial With Dollar Symbol
Humira’s loss of US exclusivity in 2023 represents the biggest opportunity yet for biosimilars • Source: Shutterstock

With long-awaited biosimilar competition to AbbVie’s top-selling Humira (adalimumab) brand finally expected to hit the US in 2023, the off-patent industry is bracing for its biggest ever loss-of-exclusivity opportunity.

While the originator has not yet reported full-year sales figures for 2022, in 2021 US Humira revenues grew by 7.6% to $17.3bn – representing a significant chunk of the brand’s global $20.7bn total – with the arthritis treatment only losing its crown as the world’s top-selling drug in 2021 when it was unseated by Pfizer/BioNTech’s Comirnaty mRNA vaccine for COVID-19

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