Stroke Prevention For TAVR – And, Perhaps, Beyond

Although TAVR-related stroke rates have been diminishing, it remains a devastating complication of the procedure. Two companies with devices to deflect or collect emboli are embarking on IDE trials that they hope will make cerebral embolic protection a standard of care in TAVR and perhaps other cardiac surgeries, as it already is in carotid artery stenting.

Transcatheter aortic valve replacement (TAVR) is a rising alternative to surgical aortic valve replacement (SAVR) in otherwise inoperable or high-risk patients with severe aortic stenosis. Its penetration into aortic valve replacement is growing fast, extending to younger and lower-risk patients, and Morgan Stanley recently predicted a $7.4 billion TAVR market by 2025. Like other left-sided heart procedures, TAVR carries a stroke risk because debris can be released into the aorta as the new valve is placed. (See[A#2014700132]and Also see "TAVR Market: Next-Generation Devices Seek To Optimize Outcomes" - Medtech Insight, 28 March, 2014..)

Although results from the ADVANCE study published in the July 21, 2015, issue of the Journal of the American College...

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