A Day of Reckoning for Aging Facilities: Is It Time to Invest in Change?

With its acquisition of Hospira, Pfizer joins the ranks of pharmaceutical companies struggling to eke out a profit from aging sterile injectables facilities without shutting them down for badly needed upgrades for fear of triggering additional drug shortages. Meanwhile, flexible, modular next-generation facilities that could add capacity where needed are on the horizon.

The quality troubles that Pfizer acquired with Hospira this month are symptoms of an aging, shortage-prone sterile injectables infrastructure that the pharmaceutical industry is preparing to resolve with new, more agile manufacturing facilities.

Pfizer is piloting a modular oral solids manufacturing system that could be adapted for sterile injectables even as other manufacturers are working to resolve the challenges of the aging sterile injectable facilities they recently acquired Also see "

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