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Novartis Previews Panobinostat PFS Advantage In Myeloma

 
• By Mary Jo Laffler

Positive Phase III findings support Novartis’ plan for filing the pan-DAC inhibitor in 2014. The firm’s initial BLA for the compound, seeking accelerated approval in Hodgkin’s lymphoma, was rejected by FDA in 2011.

Novartis AG is moving closer to bringing its first-in-class pan-deacetylase (pan-DAC) inhibitor panobinostat to market with positive pivotal results in multiple myeloma, just two years after its unsuccessful attempt to gain approval for Hodgkin’s lymphoma.

On the eve of the American Society of Hematology annual meeting, held Dec. 7-10 in New Orleans, Novartis announced that...

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• By Cathy Kelly

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