Roche’s Onartuzumab Failure Raises More Questions About How Best To Target Met

Roche’s onartuzumab (MetMab) fails in Phase III lung cancer study, raising questions about the company’s biomarker approach and the Met target more generally.

The failure of Roche’s onartuzumab (MetMab) in a targeted, Phase III advanced lung cancer study represents a blow to the company’s personalized oncology pipeline and raises questions about the future for drugs in the same class.

Roche subsidiary Genentech Inc. announced March 3 that in a planned interim analysis of the Phase III second-line/third-line MetLung...

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