Doubts Linger Over Whether AVERROES Gives Any Advantage To Apixaban

Bristol-Myers Squibb Co./Pfizer Inc. have evidence in hand that their investigational anticoagulant apixaban is useful in patients who can’t take warfarin. But any marketing gains for apixaban in this niche could be limited by physician skepticism about the patient population, assumptions that other similar drugs will be just as good in that population, and the recent FDA approval of the rival oral drug Pradaxa.