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Lipitor Watch: Pfizer Hangs On To Share, But At What Cost?

 
• By Wendy Diller

As the world enters the seventh week of generic atorvastatin, Pfizer has clearly managed to hang on to more share for the brand than it would have under a more traditional, less aggressive strategy. But there was never anything traditional about Lipitor to begin with, so it remains an open question whether another brand firm could reproduce Pfizer’s success, or even its approach, in the face of an exclusivity loss.

SAN FRANCISCO – The post-Lipitor world is evolving as expected, with the brand retaining 37% to 38% share of total prescriptions, and price discounting in line with other, similar generics launches, according to CEOs of both Pfizer Inc. and Watson Pharmaceuticals Inc.

“It’s difficult to hold on to more than that, due to pressures on pharmacies to substitute [generics],” Pfizer CEO Ian...

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More from United States

CAR-T REMS Removal Should Boost Access, But Long-Term Follow-Up, Black Box Remain

 
• By Sarah Karlin-Smith

The REMS removal and labeling changes should open up CAR-T treatment to many more US patients, although other regulatory hurdles and safety language that experts had wanted removed still stand.

America Next: Most Novel Agents With July Goal Dates Have Been Approved Overseas

 
• By Bridget Silverman

The US FDA will not be in its usual position as the first regulator to approve novel drugs, with only one of the six novel candidates on the July user fee calendar seeking its first approval worldwide in the US

PDUFA VIII: Cutting Perceived Conflict Of Interest May Be A Theme

 
• By Derrick Gingery

Ongoing questions about user fees exerting too much influence over the FDA could spawn a shift in the PDUFA structure when talks begin later this year.

US CDC Vaccine Committee Revives Thimerosal Debate: A Portent Of Things To Come?

 
• By Bridget Silverman

The new Advisory Committee on Immunization Practices voted for new recommendations on the decades-old thimerosal safety issue and lays intellectual groundwork to revisit other past controversies and decisions.

More from North America

Merck’s Clesrovimab Vote Reflects New ACIP Members’ Skepticism

 
• By Sue Sutter

The new Advisory Committee on Immunization Practices members endorsed Merck & Co.’s monoclonal antibody for RSV prevention, but some questioned its use in healthy babies and potential interactions with vaccines given at the same time.

Oz Says Big PBMs Have ‘Window’ to Quit Rebate System on Their Own

 
• By Leslie Small

CMS Administrator Mehmet Oz said PBMs may deserve "one last chance" to fix the rebate system before federal regulations and legislation are enacted.

Canada Unveils Draft List of Essential Drugs For Universal Pharmacare

 
• By Neena Brizmohun

The list of essential prescription drugs and related products will shape Canada’s first national formulary for the country’s universal pharmacare program.