MedImmune Pulling Ahead As AstraZeneca R&D Engine, Contributing Half Of Pipeline

The large-molecule specialist is delivering on the plan put in place with its 2007 acquisition, with late-stage advances in psoriasis, rheumatoid arthritis, asthma, COPD and lupus, execs say in interview with “The Pink Sheet.” Leading the way for parent company AstraZeneca in cancer immunotherapy, MedImmune says it is well positioned in that widely watched space with clinical candidates in four different mechanisms of action.

MedImmune LLC has unveiled a plethora of positive Phase II and Phase III data for large-molecule candidates in a variety of therapeutic areas lately, adding ballast to the projections of Pascal Soriot, CEO of parent AstraZeneca PLC, that his company has a pipeline offering the potential to raise annual sales revenue to more than $45 billion by 2023.

Soriot, who joined AstraZeneca from Roche in 2012 and reworked both the pipeline and R&D focus, made that claim during a May 6 investor briefing to argue that the U.K.-headquartered pharma should remain independent, rather than consider merger overtures from competitor Pfizer Inc. ([A#14140506004]). At the J.P

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