Mini Sentinel Alleviates FDA Concern Over Pradaxa Bleeding Issue

Data from the pilot program a “driving factor” in the agency’s decision against changing its recommendations for the blood thinner following reports of increased serious bleeding events.

Data from FDA’s Mini Sentinel program was among the key data used in the agency’s decision not to change its recommendations for use of Pradaxa (dabigatran) following reports of severe bleeding events.

The agency said in a Nov. 2 drug safety communication that results from a Mini Sentinel assessment indicated bleeding rates associated with new users of Boehringer Ingelheim GMBH’s Pradaxa...

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