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Intercept Stock Price Skyrockets On Continuing Stream Of Good Data For OCA Candidates

Early stop due to efficacy of NIH Phase II trial in non-alcoholic steatohepatitis could mean quick pathway to approval for compound in this unmet medical need. A growing liver disease, Intercept believes NASH is an under-recognized opportunity, which could outstrip HCV and cirrhosis as a cause of liver transplantation.

Intercept Pharmaceuticals Inc. already had good news to share with investors on its planned 2014 pipeline update call Jan. 9, but it has since realized a windfall after the NIH halted a Phase II study of lead compound obeticholic acid (OCA) in the burgeoning indication known as non-alcoholic steatohepatitis (NASH) as the compound reached its primary endpoint with high statistical significance at the trial’s mid-point.

The company already had a spell of good news. A New York-headquartered firm focused on bile acid signaling, Intercept raised...

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