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With Latest RA Deal, Janssen Seeks To Improve Outcomes With Small Molecules

Janssen gets option to Modern’s small-molecule candidates for rheumatoid arthritis that could address both the inflammatory and bone-damaging effects of the disease. An R&D exec says the compounds could be complementary to, or used in combination with, Remicade and Simponi, or as standalone RA therapies.

Under an R&D collaboration and option and licensing agreement with Modern Biosciences PLC, Janssen Biotech Inc. is seeking to bolster its rheumatoid arthritis franchise with small-molecule candidates that might provide early treatment alternatives for the disease. The deal, announced Nov. 27, is one of several that Johnson & Johnson affiliates have signed in the RA space in recent years.

Janssen gets exclusive rights to preclinical bone-protective compounds under an arrangement that includes an undisclosed upfront payment and the possibility...

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