Vertex Gears Up For Next Generation In CF Therapy

Orkambi posts sales of $131m in its first quarter on the market, reaching 35% of CF patients eligible for therapy under its label. Firm also updated investors on plans for next-generation CF drugs

Vertex Pharmaceuticals Inc.'s newest cystic fibrosis drug Orkambi (lumacaftor/ivacaftor) has exceeded Wall Street projections for prescriptions and patient starts, the company reported during its third quarter earnings call Oct. 28.

Orkambi, which combines the cystic fibrosis transmembrane conductance regulator (CFTR) gene potentiator Kalydeco (ivacaftor) with the CFTR corrector lumicaftor, obtained FDA approval on July 2 and posted sales of $131m in its first three months on the market ([A#14150702004])

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