Fabre-Kramer's Gepirone: Lots Of Studies, Not Enough Efficacy

Antidepressant's positive results in two trials were undermined by large number of negative and failed studies, FDA advisory committee concludes.

Efficacy data for Fabre-Kramer Pharmaceuticals Inc.'s gepirone in major depressive disorder fall short of the evidentiary standard needed for approval, an FDA advisory committee said Dec. 1.

In two separate 9-4 votes, the majority of Psychopharmacologic Drugs Advisory Committee members said Fabre-Kramer had not provided substantial evidence of effectiveness for gepirone extended-release, and

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