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Gilead Increases NASH Emphasis With Pickup Of Nimbus ACC Inhibitor

Nimbus Therapeutics gets $400m up front in exchange for its ACC inhibitor program for NASH and HCC, giving Gilead four different mechanisms in a field of high unmet medical need.

In what might be a chilling thought for the 20-plus other companies working to bring the first drug to market in non-alcoholic steatohepatitis (NASH), Gilead Sciences Inc. has increased its already diversified pipeline in the indication, with the announced buyout of Nimbus Therapeutics’ subsidiary Nimbus Apollo and its Phase II-ready acetyl-CoA carboxylase (ACC) inhibitor program. In the deal announced April 4, Gilead will pay $400m upfront plus earn-outs.

Nimbus Therapeutics is an LLC structured entity that establishes C corporations around computational chemistry efforts on various therapeutic targets. One...

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