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Handful Of Drugs Aim To Modify Osteoarthritis

 
• By Brenda Sandburg

Disease modifying treatments in Phase II target cartilage repair and regeneration. Sponsors are enthusiastic about FDA guidance offering to help sponsors with their programs.

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A new FDA draft guidance is casting a spotlight on a "Holy Grail" in drug development: disease-modifying treatments for osteoarthritis. While most osteoarthritis drugs in the pipeline are intended to treat pain and other symptoms, a handful seek to alter the underlying pathology and structural progression of the disease.

On Aug. 22, the agency issued a two-page guidance for sponsors developing drugs, devices or biological products for these claims. No products have been approved for treatment of structural progression...

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• By Natasha Barrow

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• By Sarah Karlin-Smith

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US ‘Most Favored Nations’ Drug Pricing Policy Will Jeopardize Innovation In Europe

 
• By Francesca Bruce

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• By Xu Hu

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