Cutting-Edge Biologics Approvals, Trials Pick Up In Korea After New Law

Novartis among the first to benefit with approvals for Zolgensma, Kymriah, and Luxturna. The new law has also enabled its first clinical trial – a Phase Ib study by Seoul National University of a CAR-T therapy for recurrent or refractory, CD19-positive, B-cell acute lymphoblastic leukemia.

Gene and cell therapy
Novartis Gets Three Approvals In Korea Under New Biologics Law • Source: Alamy

Adding to a number of cutting-edge biologics that have been approved in South Korea this year, the country has just given regulatory clearance to the first study with a regenerative medicine under new legislation implemented in September 2020 to support the development of such novel therapies.

The government has been putting a focus on fostering this type of "cutting-edge" product, which it defines as cell and gene therapies, tissue-engineered products, biotechnology-convergence products using multiple technologies (excluding those whose main function is as a medical device), and other therapies that contain cell, tissue or gene components

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