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CDC Advises Against Use Of Extended Release Opioids, Redefines High Dose

 
• By Brenda Sandburg

New clinical practice guideline recommends immediate-release opioids instead of extended-release and long-acting opioids when starting pain therapy. It specifies high dose is 50 mg morphine equivalent dose (MME) per day or higher. The 2016 guideline had set it at 90 MME/day.

Opioid prescription
CDC issues updated guideline for prescribing opioids for pain • Source: Shutterstock

The Centers for Disease Control and Prevention’s revised guideline for clinicians prescribing opioids directs them to prescribe immediate-release instead of extended-release and long-acting opioids when starting therapy for acute, subacute, or chronic pain.

The new document also describes a high dose as 50 mg morphine milligram equivalent (MME) dose per day or higher, a change from the CDC’s

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