Makena Panel Vote Adversely Influenced By Framing Of Withdrawal Question, Covis Says

‘Ad hoc narrowing’ of the final voting question by hearing officer Celia Witten prevented adcomm members from voting on Covis’ proposal to restrict the preterm birth prevention drug's indication while further study was conducted, company says.

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Covis says it was disadvantaged by the narrowing of a voting question at the Makena hearing. • Source: Shutterstock

The outcome of the October 2022 public hearing on the FDA Center for Drug Evaluation and Research’s proposal to withdraw Covis Pharma’s Makena was negatively influenced by hearing officer Celia Witten’s framing of the last voting question, the company asserts.

Covis said the Obstetrics, Reproductive and Urologic Drugs Advisory Committee (ORUDAC) “was influenced by the ad hoc narrowing” of the final voting question “such that it

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