‘Anti-Aging’ R&D? One Drug To Prevent Many Diseases Is Possible, But Endpoints First Need Outside Work, FDA’s Califf Says

So-called ‘healthspan’ products would reduce the risk of multiple diseases; Califf seems open to the idea but said industry and outside groups must first find consensus on the science.

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Multi-disease endpoints intended to support the development of products to prevent or delay chronic diseases and age-related decline need to be developed by outside parties before FDA can start to build a regulatory framework, FDA Commissioner Robert Califf advised during a 3 May webinar sponsored by the Kitalys Institute’s “Targeting Healthy Longevity 2023.”

The main topic of the “healthy longevity” discussion was the evidence needed to support regulatory endpoints for so-called “healthspan” products that slow aging, reduce the risk of multiple diseases and/or...

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