Real-Time Oncology Review Excludes Applications Needing Adcomms Or New REMS

Applications no longer need to have ‘straightforward study designs’ to qualify for RTOR, but no aspect of the submission should be likely to require a longer review time, US FDA says in a final guidance on the expedited pathway.

Starry sky
Revisions to the RTOR final guidance bring eligibility criteria more in line with those of the STAR program. • Source: Shutterstock

Only relatively uncomplicated drug or biologic applications that can be quickly reviewed are suitable for the US Food and Drug Administration’s Real-Time Oncology Review program, the agency clarifies in a guidance on the expedited pathway.

To be considered for RTOR, “no aspect of the submission is likely to require a longer review time,” such as for a new Risk Evaluation and Mitigation Strategy or an...

More from Review Pathways

More from Pathways & Standards