US FDA Developing Model Master File System To Grow Modeling, Simulation Field

Similar to drug master files, MMFs would allow models to be reused, but critical issues, such as protection of proprietary information, still must be resolved.

modeling and simulation
Model Master Files could allow models to be used in multiple applications. • Source: Shutterstock

Creators of clinical trial modeling and simulation approaches soon could have a pathway for multiple sponsors to use them, potentially streamlining drug development time and costs.

Officials in the US Food and Drug Administration’s Office of Generic Drugs are considering creating model master files, which would be similar to the drug master file (DMF) system that has been in place for years

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