Animal Testing Alternatives Need Central Office At US FDA, Science Board

Slow adoption of alternatives to animal testing in the current decentralized regulatory framework shows the need for a ‘one-stop shop’ at FDA that can provide advice, precedents and qualification programs.

Organ on a chip
Animal testing alternatives like organ on a chip soon could see more use in drug development. • Source: Shutterstock

To better handle the growth of technologies intended to reduce the need for animal testing for regulatory decisions, a US Food and Drug Administration Science Board subcommittee suggested the agency establish a new central office to oversee so-called new alternative methods (NAMs) in the commissioner’s office.

Key Takeaways
  • A US FDA Science Board report recommends establishing a central office for new alternative methods (NAMs) in the FDA commissioner’s office.

  • Slow adoption of alternatives to animal testing in the current decentralized regulatory framework would benefit from a “one-stop shop” for FDA advice, precedent and qualification programs

The New Alternative Methods Subcommittee presented its

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