CIR: Industry Working On Producing Preservative PHMB Sensitization Data

The Cosmetic Ingredient Review Expert Panel issued final safety conclusions for five ingredients at its Dec. 4-5 meeting, as well as six tentative reports and two insufficient data announcements. According to a post-meeting recap, industry is working to complete a sensitization study for preservative polyaminopropyl biguanide at the panel's request.

Triglycerides and panthenol, pantothenic acid and derivatives were among ingredient groups that received final safety determinations at the Cosmetic Ingredient Review Expert Panel's Dec. 4-5 meeting, all deemed mostly safe as used, with some caveats and cited data gaps.

In total, the industry-funded organization's team of independent experts issued five final safety conclusions, six tentative reports and two insufficient...

Read the full article – start your free trial today!

Join thousands of industry professionals who rely on HBW Insight for daily insights

  • Start your 7-day free trial
  • Explore trusted news, analysis, and insights
  • Access comprehensive global coverage
  • Enjoy instant access – no credit card required

More from Ingredients & Safety

AESGP Annual Meeting: Harmonizing EU VMS Max Levels Could Cost Sector Over €200m

 
• By 

Limited capacity and a two-to-three year timescale for reformulation could mean that many VMS supplements disappear from the market, warns EPPA partner Alexandra Bocquillion, speaking at the AESGP Annual Meeting in Warsaw, Poland.

EU Pharma Reform: Council Proposes Rx Exemption For Topical Antimicrobials

 
• By 

The EU Council has introduced a key amendment to Article 51 (para 1, point e) of the new pharma directive: “A medicinal product shall be subject to medical prescription where it is an antimicrobial, unless intended for topical use.”

Review Suggests Advantage Of Bayer’s Iberogast Advance For Digestive Disorders

 
• By 

Bayer's Iberogast Advance's combination of six herbal ingredients may produce a synergistic effect that acts on multiple underlying issues contributing to digestive disorders like functional dyspepsia (FD) and irritable bowel syndrome (IBS), a recently published study suggests.

Allergy Ingredient Itch Warning, ACNU Final Rule Scratch Extent Of FDA Authority For Label Changes

 

Effective date for ACNU OTC switch final rule and finding of severe itching from long-term use of common allergy ingredients are bookends for limits of FDA’s authority for product label changes.

More from HBW Insight

Moberg Nail Fungus Line Takes Lead In Norway As Firm Plots EU Expansion

 
• By 

Terclara - Moberg’s proprietary topical formulation of terbinafine for fungal nail - has established itself as the market leader in Norway just months after its OTC launch. The firm is now plotting its expansion to additional EU markets.

PAGB: UK Gov Must Invest In Self-Care To Realize ‘Untapped Potential’

 
• By 

Reacting to chancellor Rachel Reeves' 2025 public spending review, PAGB welcomed increased funding for healthcare and life sciences while stressing the need to promote self-care practices.

Summer Beauty: Scalp, Hair Growth Ranges, Lip Balms Under Beauty/Food Deals

 

Arbonne International’s Hair Care Collection Scalp Elixir demonstrated improvement in scalp buildup in 96% of participants in a small study. Separately, It’s a 10 Haircare has extended with a new range, F.A.S.T. Haircare, clinically proven to grow hair up to 99% faster; Beauty Launch Roundup