‘We Can’t Go Back In Time’: CIR Panel Grapples With Prostaglandins Review Without Animal Test Data

In its safety assessment of two prostaglandin analogues, the Expert Panel for Cosmetic Ingredient Safety determined that certain read-across data from potentially related ingredients were not enough to extrapolate and apply to a prostaglandin review. This and more from the panel's 4-5 December meeting.

Animal testing of cosmetic ingredients has been almost completely eliminated globally, but validated, regulatory-accepted alternative methods continue to be lacking for certain endpoints, presenting challenges that were brought into relief at the 4-5 December meeting of Cosmetic Ingredient Review experts.

CIR’s Expert Panel for Cosmetic Ingredient Safety was tasked at the meeting with reviewing ethyl tafluprostamide (ET) and isopropyl cloprostenate (IC), ingredients purported to function as lash and brow conditioning...

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