Karo Bio's future looks uncertain following news that it is dropping its Phase III-stage drug candidate eprotirome after a preclinical study demonstrated "unwanted effects following long-term exposure". As a result, the planned spin-off of the company's preclinical operations into a separate entity will not proceed.
Eprotirome, Swedish firm Karo Bio's lead programme, is a thyroid hormone receptor agonist. It had demonstrated in three Phase II...
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