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First coeliac disease vaccine moves forward in expanded clinical programme

 
• By Ian Haydock

Some of the $20 million that the US startup ImmusanT raised late last year in a Series A financing is being put to use with the start of an expanded international clinical programme for Nexvax2, its ground-breaking therapeutic vaccine for coeliac disease.One of the new placebo-controlled Phase I trials will see around 84 patients enrolled across four sites in Australia and New Zealand, in which induction of tolerance in individuals on a gluten-free diet will be assessed at multiple ascending doses.

Some of the $20 million that the US startup ImmusanT raised late last year in a Series A financing is being put to use with the start of an expanded international clinical programme for Nexvax2, its ground-breaking therapeutic vaccine for coeliac disease.One of the new placebo-controlled Phase I trials will see around 84 patients enrolled across four sites in Australia and New Zealand, in which induction of tolerance in individuals on a gluten-free diet will be assessed at multiple ascending doses.

The second new trial, in around 30 adults at four sites in the US, will look at safety, tolerability and...

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