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Regulus floats after slashing IPO price but partner placements add to tally

 
• By Mandy Jackson

Regulus Therapeutics sold 11.25 million shares of common stock at $4 per share on 4 October - one-third of its earlier expectation of $10 to $12 per share - when its initial public offering debuted on the Nasdaq, but the company raised $70 million in total thanks to a concurrent private placement of 6.25 million shares with its partner AstraZeneca.

Regulus Therapeutics sold 11.25 million shares of common stock at $4 per share on 4 October - one-third of its earlier expectation of $10 to $12 per share - when its initial public offering debuted on the Nasdaq, but the company raised $70 million in total thanks to a concurrent private placement of 6.25 million shares with its partner AstraZeneca.

With the IPO alone, Regulus garnered $45 million before fees - including at least $15 million from existing investors and partners - and the San Diego-based microRNA specialist expects to...

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Galapagos Expands Point-Of-Care CAR-T Study To The US

 
• By Andrew McConaghie

CEO Paul Stoffels said gaining US clearance for an IND for its novel CAR-T product was demanding, but now opens up a pathway towards a pivotal study starting in 2025.

Analysts Split On Eisai’s Chances Of Changing EU Regulator’s Mind On Leqembi

 
• By Andrew McConaghie

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Merus Bispecific Impresses In Head And Neck Cancer

 
• By Andrew McConaghie

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Zydus To Continue Mirabegron Sales, Looks To World-First Dual Shigella-Typhoid Vaccine

 
• By Vibha Ravi

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Challenging Environment For Biopharma Is A Tailwind For Royalty Pharma

 
• By Jessica Merrill

The royalty revenue stream acquirer has around 40 products in its portfolio and expects to generate roughly $3bn this year. Head of R&D and investments Marshall Urist talked about the investment strategy at the RBC Healthcare Conference.