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Peregrine Officially End Late-Stage Development of Bavituximab

 
• By Lisa LaMotta

The biotech continues to look for alternative data that could resurrect its lead product after a slew of failures.

After a Phase III blow-up in February, Peregrine Pharmaceuticals Inc. has finally decided what to do with its flailing immuno-oncology program, all while trying to put the focus on its more successful contract manufacturing business.

Peregrine announced June 2 that it will no longer initiate any further Phase II or Phase III clinical trials for bavituximab, but will instead conduct small early-stage studies combining the...

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One Phase III trial hits but a second study misses by a mile.

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In Brief: Neurocrine Details New Data For Schizophrenia Drug Moving To Phase III

 
• By Sushmita Panda

Neurocrine reports new details of positive Phase II results in schizophrenia and a favorable safety and cardiovascular profile for its first-in-class oral M4 agonist, now moving to Phase III trials.

Astellas Gets CLDN.18.2-Targeted ADC From China’s Evopoint

 
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Merck & Co./Daiichi Pull Patritumab Deruxtecan BLA On Disappointing OS

 
• By Jessica Merrill

Patritumab deruxtecan is the lead antibody drug conjugate in a $22bn deal signed between the two partners, with the decision marking a disappointing setback