With two new impressive Phase III trials just released, Johnson & Johnson's monoclonal antibody Darzalex (daratumumab) is solidifying the role of anti-CD38 antibodies in multiple myeloma, but other new classes are emerging and could further shake up the treatment space, researchers say.
Another Sea Change In Myeloma Promised By New Therapies, Combos
Darzalex made a splash with impressive Phase III data in relapsed multiple myeloma at the EHA and ASCO meetings, but a range of other drugs are on the way, including a next-generation CD38 inhibitor from Sanofi, checkpoint inhibitors and Roche's BCL-2 Venclexta.
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