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Merck Poised To Be First To Market With A PD-1 For First-Line Lung Cancer

 
• By Jessica Merrill

Merck’s Keytruda improved progression-free survival and overall survival in previously untreated non-small cell lung cancer patients in the highly-anticipated KEYNOTE-024 trial, all but guaranteeing a rapid FDA approval in the indication.

Positive progression-free survival and overall survival data from Merck & Co. Inc.’s high profile KEYNOTE-024 trial testing Keytruda (pembrolizumab) in patients with previously untreated advanced non-small cell lung cancer (NSCLC) positions Keytruda to beat Bristol-Myers Squibb Co.’s Opdivo (nivolumab) to a first-line lung cancer indication.

The winner long-term in the high stakes market remains very much up in the air, however, as the details of...

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In Brief: 4DMT Fast-Tracks Long-Acting Wet AMD Therapy Trials, Cuts 25% Of Workforce

 
• By Sushmita Panda

4D Molecular Therapeutics has fast-tracked its Phase III trials for 4D-150 in wet AMD, with top-line data from one now expected in H1 2027 and another underway ahead of schedule. The company is also cutting a quarter of its staff as it focuses on its late-stage pipeline and to help fund the trials.

Beyond AI Hype: Tokyo-1’s Real Answer On How To Innovate Pharma R&D

 
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In Brief: Atai-Beckley Deal Marches On After Phase II Psychedelic Win

 
• By Manas Mishra

The psychedelic therapy firms pass a key condition for their planned merger after the antidepressant BPL-003 meets the main endpoints of a Phase IIb trial.