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German Merck Identifies Pipeline Stars, Plots Course Through A Dynamic Cancer Space

 
• By Alexandra Shimmings

As questions remain over Merck KGAA's ability to retain its top line following the patent loss for its key products Rebif and Erbitux, the German company has highlighted some of its higher priority R&D programs in its "very interesting" pipeline, as well as its strategy to make the most of the assets.

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After several years with no new product launches, Merck KGAA is expected to announce imminently the EU filing for its much-delayed multiple sclerosis treatment cladribine, and will supplement this with another submission for its key immune-oncology offering, avelumab, later this year. However, further cladribine filings including in the US will await further discussions with regulators, with the company not prepared to share any timelines yet.

Speaking to analysts on June 20, Merck's chief marketing and strategy office for healthcare, Rehan Verjee, said that over the...

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Pfizer and Arvinas have agreed to out-license their PROTAC breast cancer candidate, vepdegestrant, with Arvinas cutting jobs and refocusing on early-stage assets.

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Regeneron’s Garetosmab May Become Second Drug For Rare Bone Disease FOP

 
• By Alaric DeArment

The company announced positive Phase III data for the drug in fibrodysplasia ossificans progressiva, as well as Phase II combination data among patients with obesity.