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First European Cell Therapy Is Commercial Flop

 
• By Sukaina Virji

The first cell-based product to be approved in Europe, the TiGenix-developed and Sobi-marketed ChondroCelect, has met an ignominious end with the withdrawal of its marketing authorization. However, TiGenix has entered into an agreement with Takeda for ex-US rights to its next product candidate.

TiGenix NV of Belgium has begun the process of withdrawing the marketing authorization for ChondroCelect, an autologous chondrocyte-based cell therapy for the treatment of cartilage lesions of the knee, due to "commercial reasons."

The decision had been made due to the difficult competitive landscape resulting from a tough regulatory environment around such products...

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