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Peptimmune Inc.

 
• By Mary Stuart

By intervening at the level of antigen processing and presentation, Peptimmune aims to develop drugs that downregulate the inappropriate immune response that occurs in such autoimmune disorders as multiple sclerosis and rheumatoid arthritis and to boost the response in the case of HIV and other viruses.

The goal of several companies working in autoimmune diseases is to selectively suppress disease-causing T-cells, thereby interrupting the complex cascade of immunological reactions very early in the process, before damaging inflammatory events occur. These development efforts are attempting to intervene upstream of the junctures at which the currently available drugs interact, or, "at the headwaters of the immune system," according to Peptimmune Inc. 's president and co-founder Ben Bronstein.

By intervening at the level of antigen processing and presentation, Peptimmune aims to develop drugs that downregulate the inappropriate immune...

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Final Chance To Have Your Say: Take Scrip's Reader Survey This Week

 
• By Eleanor Malone

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• By Andrew McConaghie

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• By Andrew McConaghie

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• By Jessica Merrill

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CEO Underlines AstraZeneca’s Increasingly US-Centric Growth Plans

 
• By Andrew McConaghie

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Analysts Not Impressed With Adaptimmune’s Survival Attempts

 
• By Kevin Grogan

The company is getting just $55m from the sale of Tecelra and a couple of late-stage T-cell therapies to US WorldMeds.