TheraMed Inc.

To carry on work focusing on the oxygen-delivering capacity of red blood cells, EntreMed Inc, (best known for its anti-angiogenic molecules) created spin-off TheraMed Inc. TheraMed has developed a prototype device and is experimenting with different sorts of reagents, which it believes will enable the three basic sorts of blood cells--platelets, red cells and white blood cells--to be transformed into delivery vehicles for oxygen, drugs, and genes.

Although EntreMed Inc. is now best known for developing anti-angiogenic molecules such as endostatin, the company did not actually begin life with the goal of commercializing that molecule, which sparked a huge run on the company's stock in May 1998, while it was still being tested in mice as an anti-tumor agent.

One of EntreMed's original goals was to enhance the oxygen-delivering capacity of red blood cells, via a method of causing...

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