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MBT Munich Biotechnology GMBH

 
• By Melanie Senior

MBT Munich Biotechnology is developing cancer diagnostics and therapeutics that it hopes will allow early tumor detection along with localized, lower-dose and safe cancer treatments. Its technology is based on the encapsulation of different compounds into positively charged liposomes that it calls "catioms."

Research into angiogenesis—the growth of new blood vessels—has become an important approach to finding new cancer treatments. But identifying compounds that target and destroy tumor cells, without affecting healthy surrounding tissue, has proved difficult. Tumors in humans are more complex than those in mice and other animal models, and can develop resistance to certain drugs. Cytotoxic treatments such as Bristol-Myers Squibb Co.'s blockbuster paclitaxel (Taxol), although effective, have considerable side effects. Another challenge has been to identify and locate tumors—either directly or via related markers—early enough for effective treatment and cure.

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