Data mining start-up ReceptorBase Inc. has been validating its service model by prospecting GPCRs, a family of receptors known to hold more pharmaceutical riches than any other. Focusing on receptor protein function, the company applies empirical data from known small molecules to search out atomic binding sites. It then uses proprietary computational methods to predict compound designs that are mostly likely to hit the right target.
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CEO Paul Stoffels said gaining US clearance for an IND for its novel CAR-T product was demanding, but now opens up a pathway towards a pivotal study starting in 2025.
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