Five Prime Therapeutics Inc.

The model of this well-financed two-year-old start-up harks back to the mid-to-late 1990s when technology promised to provide industrial-age solutions to the handcraft of drug R&D. Its investor list likewise recalls earlier years: one of its key venture funds, Kleiner Perkins, once at the forefront of biotech investing has largely remained on the sidelines since the mid-1990s. Even its vocabulary echoes older ambitions--FivePrime aims to mine the pharmanome, just as companies in the late 1990s aimed to mine the proteome, peptidome, metabolome, cytome, glycome and cellome.

951 Gateway Boulevard

South San Francisco, CA 94080

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