The model of this well-financed two-year-old start-up harks back to the mid-to-late 1990s when technology promised to provide industrial-age solutions to the handcraft of drug R&D. Its investor list likewise recalls earlier years: one of its key venture funds, Kleiner Perkins, once at the forefront of biotech investing has largely remained on the sidelines since the mid-1990s. Even its vocabulary echoes older ambitions--FivePrime aims to mine the pharmanome, just as companies in the late 1990s aimed to mine the proteome, peptidome, metabolome, cytome, glycome and cellome.
951 Gateway Boulevard
South San Francisco, CA 94080
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Also deals involving Xspray/Handa, Fosun/Expedition, Kaken/Astria, Orchid/Allecra, Sanofi/Visirna, KKR/Healthcare Royalty Partners, Viridian/Kissei, Sandoz/Evotec, Dx&Vx, Dr. Falk/Allianthera, Madrigal/CSPC and Lilly/LTZ.
Lupin is hoping moves like intellectual property transfer for some products to the US will help mitigate the tariff impact even as it counts on growth from planned launches of GLP-1s and biosimilars while riding high on tolvaptan launched in Q1.
The French drugmaker's anti-CD38 antibody has racked up another approval in first-line multiple myeloma, but it marks a small victory while the company develops a subcutaneous version to help level the field with J&J’s Darzalex.
Royalty deals are on track for another blowout year, but it’s not only because of a depressed biotech market. Large investment firms such as KKR are taking note.
Most major Japanese firms report generally positive fiscal first quarter results, led by mainstay growth and despite lower currency effects. But the future impact of any US pharma tariffs remains an overhang.
Deal Snapshot: Bayer will take over development of the asset once Kumquat completes a Phase Ia clinical trial, but the biotech firm may opt in to share US profits and losses.
Madrigal and Syndax update investors on their key launches, while Merck KGaA weighs in on the possibility of direct-to-consumer sales in the US.
