Unlike for other tissues and organs in the body, no good cell culture model of the liver exists. This difficulty has hampered the discovery of therapeutics for a wide variety of liver diseases-hepatitis, cancer, and cirrhosis, for example-but Hepaticus Inc. is planning to change this: the firm has devised a way to model human liver cell functionality using immunocompetent rats.
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The China Securities Regulatory Commission has proposed a new “growth tier” for the STAR Market of the Shanghai Stock Exchange, to reinstate the market’s listing standards for unprofitable firms.
Highlights from Day Four of the BIO International Convention include Woodcock offering practical advice on rare disease trials, the sorry state of dealmaking mid-year, Novartis discussing its approach to partnering, and Generate looking for funding to move into Phase III.
While some are calling for Syncona to be wound up, the UK-based company believes many existing and new investors will back the creation of new private fund.
