Delivering compounds across the blood-brain barrier remains the rate limiting step in brain-drug development, yet the problem generally gets ignored until it's too late. Several biotechs are bringing novel strategies to finding a solution, focusing especially on brain cancers. Success may open the floodgates of CNS drug development.
Marc Wortman
The blood-brain barrier gets no respect. It should. Fewer than 2% of drugs have the requisite properties to get across...
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