Next-gen sequencing start-up Eureka Genomics says its novel algorithms and data structures are especially effective for the analysis of large sets of short genomic subsequences. The company can analyze sequencing data for non-host genetic material, such as bacteria or viruses. It can also design ultraspecific signature sequences that can be used to detect pathogens or ganisms of interest. In addition to its sequencing service business, Eureka intends to generate novel diagnostics, therapeutic targets and possible vaccines based on microorganisms associated with disease.
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CEO Paul Stoffels said gaining US clearance for an IND for its novel CAR-T product was demanding, but now opens up a pathway towards a pivotal study starting in 2025.
A final rejection of Leqembi could also spell the same fate for Lilly’s rival drug but public outcry and demand for Alzheimer’s therapies might force the regulator’s hand
Regeneron is bringing in its own GIP/GLP-1 agonist, establishing a path to develop proprietary obesity drug combinations with its internal muscle-sparing drugs.
Data from AstraZeneca/Daiichi’s breast cancer trial showed positive PFS, but some oncologists are waiting for confirmation of statistically significant OS benefit.
But the French major is still keen on early-stage M&A.
