Just over a year old at the start of June 2011, Tesaro Inc. raised a Series B financing of $101 million. This largest biotech venture financing of the year has enabled the company to start building its oncology pipeline, starting with the December 2010 in-licensing of rolapitant, a Phase III-ready drug candidate for chemotherapy-induced nausea and vomiting.
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CEO Paul Stoffels said gaining US clearance for an IND for its novel CAR-T product was demanding, but now opens up a pathway towards a pivotal study starting in 2025.
A final rejection of Leqembi could also spell the same fate for Lilly’s rival drug but public outcry and demand for Alzheimer’s therapies might force the regulator’s hand
Insights from Novotech on Evolving Trends Impacting Global Clinical Development
In this week's episode: Novo Nordisk’s CEO forced out; quantifying biopharma’s contribution to the US economy; a history of MASH deals; lift for AstraZeneca’s asthma ambitions; and major Japanese firms see US revenue growth.
Sun readies US debut of Leqselvi for alopecia areata, while PD-L1 inhibitor Unloxcyt is in the line up once the Checkpoint Therapeutics deal is completed. Management also discusses limited clarity on President Trump’s most favored nation pricing push, pipeline tweaks and M&A outlook.
