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EPIC Fail For Mast Therapeutics’ Lead Drug Sends Shares Into Freefall

 
• By Alexandra Shimmings

Shares in Mast Therapeutics dropped by more than 80% upon news that a Phase III trial of its lead product vepoloxamer in sickle cell disease had failed.

Sickle cell anemia, 3D illustration showing blood vessel with normal and deformated crescent-like red blood cells
• Source: Shutterstock, Kateryna Kon

San Diego, California-based Mast Therapeutics Inc. is pinning its hopes on its vasodilating AIR001 program for heart failure following the second Phase III failure for its sickle cell disease candidate vepoloxamer.

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• By Andrew McConaghie, Edwin Elmhirst, and Dexter Jie Yan

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Henlius In David Versus Goliath Race With Pfizer For First PD-L1 ADC

 
• By Dexter Jie Yan

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AstraZeneca Logs Japan Growth Despite Price Cuts

 
• By Lisa Takagi

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