1. Scrip
  2. >>R&D

ESMO Preview: Opdivo Under Pressure

 
• By Sukaina Virji

All eyes will be on beleaguered Opdivo at ESMO 2016 as BMS's leading checkpoint inhibitor comes under scrutiny in the NSCLC and renal cell cancer space. Details of Merck & Co's KEYNOTE-024 trial, Roche's Tecentriq in lung cancer and Exelixis' cabozantinib in kidney cancer could impact on how Opdivo's prospects are viewed.

Scrip, with help from Datamonitor Healthcare analyst Rachael Lloyd, has identified a number of clinical trial data presentations due at ESMO 2016 (the annual meeting of the European Society of Medical Oncology) that will help to shape the commercial future of Bristol-Myers Squibb Co.'sOpdivo (nivolumab).

Opdivo currently dominates the NSCLC setting owing to its approval in the second line setting independent of PD-L1 status. However,...

Read the full article – start your free trial today!

Join thousands of industry professionals who rely on Scrip for daily insights

  • Start your 7-day free trial
  • Explore trusted news, analysis, and insights
  • Access comprehensive global coverage
  • Enjoy instant access – no credit card required
Start Free Trial

Already a subscriber?

More from R&D

Sanofi Revels In More Positive Rilzabrutinib Data

 
• By Kevin Grogan

The oral BTK inhibitor impresses in a Phase II trial for IgG4-related disease.

Is Zydus’s Agenus Deal Opportunistic Or Strategic?

 
• By Vibha Ravi

Will Zydus’s acquisition and licensing deal with Agenus turn out to be a strategic move towards building an oncology portfolio or an opportunistic one driven by a venture capital mindset?

How AstraZeneca Aims To Stay Ahead In Lupus As New Competition Looms

 
• By Andrew McConaghie

The company has established the efficacy of its biologic Saphenlo in systemic lupus erythematosus but is now investing across modalities to stay ahead of rivals.

Biogen Lays Out Cadence For Felzartamab Data In Kidney Diseases

 
• By Jessica Merrill

The first Phase III data for the CD38-targeting antibody is expected in 2027 in antibody-mediated rejection in kidney transplant patients, followed by other indications.

More from Scrip

BioNTech To Buy mRNA Rivals CureVac

 
• By Andrew McConaghie

The $1.25bn buyout is a simple deal for BioNTech, bringing new mRNA R&D and manufacturing capacity while also ending a bothersome patent dispute.

Is Zydus’s Agenus Deal Opportunistic Or Strategic?

 
• By Vibha Ravi

Will Zydus’s acquisition and licensing deal with Agenus turn out to be a strategic move towards building an oncology portfolio or an opportunistic one driven by a venture capital mindset?

How AstraZeneca Aims To Stay Ahead In Lupus As New Competition Looms

 
• By Andrew McConaghie

The company has established the efficacy of its biologic Saphenlo in systemic lupus erythematosus but is now investing across modalities to stay ahead of rivals.