Allergan Up For Alzheimer's Challenge With Chase Buy

Allergan is paying $125m for Chase Pharmaceuticals and its Alzheimer's disease candidate CPC-201 that has completed Phase II testing. The modest upfront reflects the Phase III graveyard that Alzheimer's disease represents. Chase is led by two former Allergan executives.

Allergan PLC has acquired Chase Pharmaceuticals Corp. for an upfront payment of $125m plus potential regulatory and commercial milestones of up to $875m to Chase's shareholders. These include India's Cipla Ltd., which held a 16.7% stake in the firm.

Chase's lead compound, CPC-201, is a patent-protected combination of the most commonly prescribed acetylcholinesterase inhibitor donepezil and the peripherally acting...

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