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Broad-Based Incyte/Merus Collaboration Includes Up To 11 Bispecific Antibody Programs

 
• By Joseph Haas

The US biotech is paying $200m up front in cash and equity investment for the ability to use Merus’ bispecific technology platform in up to 11 programs, which could move beyond cancer and include novel targets and biology. Potential earn-outs under the deal could reach nearly $3bn.

Incyte Corp. and Merus BV have announced a broad-based bispecific antibody discovery, development and commercialization partnership that could include up to 11 programs, result in potential earn-outs to Merus of nearly $3bn and includes the flexibility to move into novel targets and novel biology.

On a Dec. 21 conference call, Merus executives called the agreement “truly transformative” in that it validates the company’s Biclonics bispecific antibody technology platform, while providing a major cash infusion and leaving the Dutch firm with full rights to its two clinical candidates and one of its most advanced preclinical candidates, all in the immuno-oncology space

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