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Intercept’s NASH Phase III Enrolling Slowly; Gilead Could Gain Ground

 
• By Joseph Haas

As Gilead’s ASK1 inhibitor nears Phase III, Intercept may be plagued by slower-than-expected enrollment of its Phase III trial for Ocaliva. A recent Biomedtracker survey finds liver docs may be more positively inclined toward the Gilead candidate.

Liver

Gilead Sciences Inc.’s announcement at the J.P. Morgan Healthcare Conference that it will take its lead candidate for non-alcoholic steatohepatitis, the apoptosis signal-regulating kinase-1 (ASK1) inhibitor selonsertib, into Phase III soon is shaking up the NASH race.

It’s premature to predict anything approaching a tectonic shift, but Gilead’s announcement opens up the possibility that the virology powerhouse...

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