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J&J's Actelion Courtship Seen Unaffected By Macitentan MAESTRO Failure

 
• By Sten Stovall

Johnson & Johnson is expected to keep pursuing Actelion despite news the target's pulmonary arterial hypertension drug macitentan missed a primary endpoint in a Phase III study of patients with PAH due to Eisenmenger Syndrome.

Gannets

Johnson & Johnson will likely shrug off failure of a late-stage study using Actelion's Opsumit (macitentan) in patients with pulmonary arterial hypertension due to Eisenmenger Syndrome and keep pursuing M&A talks aimed at buying Europe’s largest biotech company, analysts said.

Actelion Pharmaceuticals Ltd.Jan. 23 said the MAESTRO Phase III trial of Opsumit failed to demonstrate a benefit for the drug in Eisenmenger syndrome, a congenital heart defect

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